Intraoperative radiotherapy: Patient selection, management, and follow-up

J Surg Oncol. 2017 Dec;116(7):824-830. doi: 10.1002/jso.24734. Epub 2017 Jul 17.


Intraoperative partial breast radiotherapy is an alternative or an adjunct to fractionated whole breast irradiation for the administration of adjuvant radiotherapy in breast cancer following breast conserving surgery. Establishing intraoperative radiotherapy as a therapeutic modality requires a multidisciplinary approach to patient selection, workup, surgery, radiation protocols, chemotherapy, and patient follow up. In this article, we review the published evidence for best clinical practice, as a guide to the introduction of intraoperative radiotherapy for breast cancer treatment.

Keywords: breast conserving surgery; breast irradiation; intraoperative radiotherapy.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / radiotherapy*
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Intraoperative Care / methods
  • Patient Selection