The autonomic nervous system in congestive heart failure

Annu Rev Med. 1986;37:235-47. doi: 10.1146/annurev.me.37.020186.001315.

Abstract

Congestive heart failure is a complex clinical syndrome characterized by striking abnormalities of the autonomic nervous system. The mechanisms and biological importance of these disturbances are not clearly defined. Nonetheless, it is possible that autonomic disturbances play an important role in the pathophysiology and prognosis of heart failure, and therefore drugs that alter autonomic function may provide additional therapeutic options in the management of this syndrome.

Publication types

  • Review

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Alprazolam
  • Animals
  • Autonomic Nervous System / physiopathology*
  • Benzodiazepines / therapeutic use
  • Blood Vessels / innervation
  • Bromocriptine / therapeutic use
  • Cardiovascular Agents / therapeutic use
  • Catecholamines / metabolism
  • Clonidine / therapeutic use
  • Cricetinae
  • Dogs
  • Dopamine / analogs & derivatives
  • Guanabenz / therapeutic use
  • Heart / innervation
  • Heart / physiopathology
  • Heart Failure / blood
  • Heart Failure / drug therapy
  • Heart Failure / metabolism
  • Heart Failure / physiopathology*
  • Hemodynamics
  • Humans
  • Myocardium / metabolism
  • Norepinephrine / blood
  • Physical Exertion
  • Posture
  • Prognosis
  • Receptors, Adrenergic / physiology
  • Reflex
  • Stress, Physiological / physiopathology
  • Sympathetic Nervous System / drug effects
  • Sympathetic Nervous System / physiopathology

Substances

  • Adrenergic beta-Antagonists
  • Cardiovascular Agents
  • Catecholamines
  • Receptors, Adrenergic
  • Benzodiazepines
  • Bromocriptine
  • N-n-propyl-N-n-butyl-beta-dopamine
  • Guanabenz
  • Clonidine
  • Dopamine
  • Norepinephrine
  • Alprazolam