Using a large, passive, febrile surveillance program in Iquitos, Peru, we retrospectively tested human blood specimens for scrub typhus group orientiae by ELISA, immunofluorescence assay, and PCR. Of 1,124 participants, 60 (5.3%) were seropositive, and 1 showed evidence of recent active infection. Our serologic data indicate that scrub typhus is present in the Peruvian Amazon.
Keywords: ELISA; IFA; Orientia tsutsugamushi; PCR; Peru; Peruvian Amazon; bacteria; immunofluorescence assay; rickettsia; scrub typhus; serologic analysis; vector-borne infections; zoonoses.