Understanding the genetics behind complex human disease with large-scale iPSC collections

Genome Biol. 2017 Jul 20;18(1):135. doi: 10.1186/s13059-017-1276-1.


Three recent studies analyzing large-scale collections of human induced pluripotent stem cell lines provide valuable insight into how genetic regulatory variation affects cellular and molecular traits.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Differentiation
  • Disease*
  • Genetic Variation*
  • Humans
  • Induced Pluripotent Stem Cells*
  • Models, Genetic*