Genetics in an isolated population like Finland: a different basis for genomic medicine?

J Community Genet. 2017 Oct;8(4):319-326. doi: 10.1007/s12687-017-0318-4. Epub 2017 Jul 20.


A unique genetic background in an isolated population like that of Finland offers special opportunities for genetic research as well as for applying the genetic developments to the health care. On the other hand, the different genetic background may require local attempts to develop diagnostics and treatment as the selection of diseases and mutations differs from that in the other populations. In this review, we describe the experiences of research and health care in this genetic isolate starting from the identification of specific monogenic diseases enriched in the Finnish population all the way to implementing the knowledge of the unique genetic background to genomic medicine at population level.