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Review
. 2018;25(40):5613-5630.
doi: 10.2174/0929867324666170720165005.

Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants

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Review

Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants

Jack Ho Wong et al. Curr Med Chem. .

Abstract

The purpose of this account is to review the compounds capable of eliciting mitochondria-mediated apoptosis in cancer cells produced by medicinal fungi and plants. The medicinal fungi discussed encompass Cordyceps, Ganoderma species, Coriolus versicolor and Hypsizygus marmoreus. The medicinal plants discussed comprise Astragalus complanatus, Dendrobium spp, Dioscorea spp, Glycyrrhiza spp, Panax notoginseng, Panax ginseng, and Momordica charantia. These compounds have the potential of development into anticancer drugs.

Keywords: Medicinal fungi; anticancer; apoptosis; medicinal plants; mitochondria..

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