Western Dietary Pattern Is Associated With Severe Coronary Artery Disease

Angiology. 2018 Apr;69(4):339-346. doi: 10.1177/0003319717721603. Epub 2017 Jul 21.


The independent predictive value of an unhealthy diet on the severity of coronary artery disease (CAD) requires further investigation. We assessed the impact of dietary pattern on CAD severity. In this cohort study, we included 188 symptomatic stable patients with CAD. Patients were categorized as having severe CAD or nonsevere CAD by coronary angiography. Among several demographics and clinical characteristics, all patients were tested using a semiquantitative food frequency questionnaire. Concerning baseline demographic characteristics, there was no difference between patients with severe CAD and nonsevere CAD. Principal component analysis revealed 8 distinct dietary patterns. The first component Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001). In conclusion, an unhealthy Western type of diet is associated with the severity of coronary artery lesions in patients with stable CAD. These findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD.

Keywords: Western type of diet; atherosclerosis; carbohydrates; coronary artery disease; fat.

MeSH terms

  • Aged
  • Cohort Studies
  • Coronary Angiography
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / etiology*
  • Diet, Western / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Principal Component Analysis
  • Risk Factors
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Surveys and Questionnaires