Review of Extracorporeal Membrane Oxygenation and Dialysis-Based Liver Support Devices for the Use of Nephrologists

Am J Nephrol. 2017;46(2):139-149. doi: 10.1159/000479342. Epub 2017 Jul 22.


Acute kidney injury in the intensive care unit (ICU) is a manifestation of an underlying severe illness that commonly involves other organ systems. Pulmonary, cardiac, and hepatic failures are the most prevalent. This article provides a simplified review of the technical aspects of extracorporeal cardiopulmonary and liver support devices used in the adult ICU patient, as well as a summary of the most relevant and up-to-date clinical evidence that supports their use.

Keywords: Continuous renal replacement therapy; Extracorporeal membrane oxygenation; Molecular adsorbent recirculation support; Prometheus liver support device; Selective cytopheretic device; Single pass albumin dialysis.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / therapy*
  • Adult
  • Extracorporeal Membrane Oxygenation / instrumentation*
  • Extracorporeal Membrane Oxygenation / methods
  • Humans
  • Intensive Care Units
  • Liver Failure, Acute / etiology
  • Liver Failure, Acute / therapy*
  • Nephrologists
  • Nephrology / methods
  • Renal Dialysis / instrumentation*
  • Renal Dialysis / methods
  • Shock, Septic / complications
  • Shock, Septic / therapy*