Experimental analysis of antihypertensive properties of S 5984 and its constituents: tertatolol and indapamide

Drugs Exp Clin Res. 1985;11(10):709-15.

Abstract

S 5984 is a combination of tertatolol (S 2395-1) and indapamide. A positive synergism between these two constituents with regard to antihypertensive activity was demonstrated in the rat and the dog.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / pharmacology*
  • Animals
  • Blood Pressure / drug effects*
  • Desoxycorticosterone / pharmacology
  • Diuretics / pharmacology*
  • Dogs
  • Drug Combinations / pharmacology
  • Indapamide / pharmacology*
  • Male
  • Propanolamines / pharmacology*
  • Rats
  • Rats, Inbred Strains
  • Thiophenes*

Substances

  • Adrenergic beta-Antagonists
  • Diuretics
  • Drug Combinations
  • Propanolamines
  • Thiophenes
  • S 5984
  • Desoxycorticosterone
  • tertatolol
  • Indapamide