Cell autonomous sonic hedgehog signaling contributes to maintenance of retinal endothelial tight junctions

Exp Eye Res. 2017 Nov:164:82-89. doi: 10.1016/j.exer.2017.07.014. Epub 2017 Jul 22.

Abstract

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Cattle
  • Cell Membrane Permeability / drug effects
  • Cells, Cultured
  • Disease Models, Animal
  • Electric Impedance
  • Endothelial Cells / drug effects
  • Endothelial Cells / physiology*
  • Hedgehog Proteins / physiology*
  • Retina / drug effects
  • Retina / physiology*
  • Signal Transduction / drug effects
  • Signal Transduction / physiology*
  • Tight Junctions / drug effects
  • Tight Junctions / physiology*
  • Vascular Endothelial Growth Factor A / pharmacology
  • Veratrum Alkaloids / pharmacology

Substances

  • Hedgehog Proteins
  • Vascular Endothelial Growth Factor A
  • Veratrum Alkaloids
  • cyclopamine