Primary Neuroendocrine Tumor of the Orbit Presenting With Acute Proptosis

Ophthalmic Plast Reconstr Surg. 2018 Jan-Feb;34(1):e17-e19. doi: 10.1097/IOP.0000000000000968.


Primary neuroendocrine tumors of the orbit are exceedingly rare and typically present with gradual, progressive exophthalmos. In this report, an otherwise healthy 64-year-old woman undergoes resection of a well-differentiated neuroendocrine tumor after presenting with acute proptosis. An extensive clinical and radiographic evaluation reveals no other evidence of disease, establishing the diagnosis of a primary neuroendocrine tumor. The case presentation is followed by a brief review of the classification, presentation, and evaluation of orbital neuroendocrine tumors.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Exophthalmos / diagnosis
  • Exophthalmos / etiology*
  • Exophthalmos / surgery
  • Humans
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / complications*
  • Neuroendocrine Tumors / diagnosis
  • Neuroendocrine Tumors / surgery
  • Ophthalmologic Surgical Procedures / methods
  • Orbit / diagnostic imaging*
  • Orbit / surgery
  • Orbital Neoplasms / complications*
  • Orbital Neoplasms / diagnosis
  • Orbital Neoplasms / surgery
  • Tomography, X-Ray Computed