Follicular porokeratosis: four new cases

Clin Exp Dermatol. 2017 Dec;42(8):881-886. doi: 10.1111/ced.13195. Epub 2017 Jul 27.

Abstract

Porokeratosis, a disorder of keratinisation, is clinically characterized by the presence of annular plaques with a surrounding keratotic ridge. Clinical variants include linear, disseminated superficial actinic, verrucous/hypertrophic, disseminated eruptive, palmoplantar and porokeratosis of Mibelli (one or two typical plaques with atrophic centre and guttered keratotic rim). All of these subtypes share the histological feature of a cornoid lamella, characterized by a column of 'stacked' parakeratosis with focal absence of the granular layer, and dysmaturation (prematurely keratinised cells in the upper spinous layer). In recent years, a proposed new subtype, follicular porokeratosis (FP_, has been described, in which the cornoid lamella are exclusively located in the follicular ostia. We present four new cases that showed typical histological features of FP.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Hair Follicle / pathology*
  • Humans
  • Lentigo / complications
  • Lentigo / pathology
  • Male
  • Middle Aged
  • Porokeratosis / classification
  • Porokeratosis / complications
  • Porokeratosis / pathology*
  • Skin / pathology*