Recent advances in the treatment of erectile dysfunction

Postgrad Med J. 2017 Nov;93(1105):679-685. doi: 10.1136/postgradmedj-2016-134073. Epub 2017 Jul 27.


Erectile dysfunction (ED) is one of the most common conditions affecting middle-aged and older men. Nearly every primary care physician, internist and geriatrician will be called upon to manage this condition or to make referrals to urologists, endocrinologists and cardiologists who will assist in the treatment of ED. This article will briefly discuss the diagnosis and management of ED. In addition, emerging concepts in ED management will be discussed, such as the use of testosterone to treat ED, the role of the endothelium in men with ED and treating the partner of the man with ED. Finally, future potential therapies for ED will be discussed.

Keywords: androgen deficiency; cardiovascular disease; endothelial dysfunction; erectile dysfunction; gene therapy; stem cells; testosterone; testosterone deficiency; testosterone replacement.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Comorbidity
  • Endothelium, Vascular / physiopathology
  • Erectile Dysfunction / diagnosis*
  • Erectile Dysfunction / etiology
  • Erectile Dysfunction / physiopathology
  • Erectile Dysfunction / therapy*
  • Humans
  • Male
  • Middle Aged
  • Polypharmacy
  • Risk Factors