Risk of carcinoma following gastric operations for benign disease. A historical cohort study of 3470 patients

Lancet. 1986 Aug 30;2(8505):502-5. doi: 10.1016/s0140-6736(86)90368-5.


The risk of stomach cancer was analysed in a cohort of 3470 patients who had had gastric surgery for benign disease between 1900 and 1969. In 87 patients (2.2%) stomach-stump cancer was diagnosed in the follow-up period 1970-84. By comparison with the total incidence of stomach cancer in the same region during the same time period, the observed versus expected ratio in the post-surgery group was 2.1 (p less than 0.001) and did not differ between men and women. At 5-10 years postoperative the risk of cancer was no different from that in the total population, whereas after 40-45 years it was 7.3-fold higher. The risk was unrelated to primary diagnosis or type of operation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Female
  • Gastrectomy / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Norway
  • Postoperative Complications*
  • Retrospective Studies
  • Risk
  • Sex Factors
  • Stomach Diseases / surgery*
  • Stomach Neoplasms / epidemiology
  • Stomach Neoplasms / etiology*
  • Time Factors