Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and Patients with Chronic Obstructive Pulmonary Disease

Am J Respir Crit Care Med. 2018 Mar 1;197(5):665-668. doi: 10.1164/rccm.201706-1304LE.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Animals
  • DNA Damage / genetics*
  • Down-Regulation / genetics*
  • Female
  • Humans
  • Lung / physiopathology
  • Male
  • Mice
  • Mice, Inbred C57BL
  • MicroRNAs / genetics*
  • Middle Aged
  • Polymerase Chain Reaction
  • Pulmonary Disease, Chronic Obstructive / genetics*
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Smokers
  • Smoking / genetics*
  • Smoking / physiopathology

Substances

  • MIRN126 microRNA, human
  • MIRN126 microRNA, mouse
  • MicroRNAs