State of the Art: Vest Nile Virus Circulation Surveillance in Italy and Transfusion Risk Early Prevention Methods

Transfus Clin Biol. 2017 Sep;24(3):172-175. doi: 10.1016/j.tracli.2017.06.019. Epub 2017 Jul 25.


After the Chikungunya outbreak in 2007 in Italy, a national Plan for the surveillance of human vector-borne diseases has been implemented and annually updated on the basis of the epidemiological changes based-evidences. The transfusion Authorities cooperates, since 2008, with public health services and veterinary (entomological and ornithological) surveillance systems. In some Italian regions, a common protocol for exchanging data is in place to identify the West Nile Virus (WNV) circulation in birds and mosquitoes: the goal is to anticipate the introduction of WNV-NAT screening in blood donors and, on the other hand, to limit testing only in geographic areas where the virus circulation is actual. The integration of surveillance activities and a multidisciplinary approach made it possible to introduce efficient and preventive measures for reducing the risk of of transmission of WNV trough blood, tissues and organ donation.

Keywords: Blood donor screening; Dépistage du donneur de sang; Risque transfusionnel; Surveillance; Transfusional risk; Virus West Nile; West Nile Virus.

Publication types

  • Review

MeSH terms

  • Animals
  • Birds / virology
  • Blood Donors
  • Blood Safety
  • Culicidae / virology
  • Disease Outbreaks
  • Disease Reservoirs
  • Donor Selection
  • Humans
  • Insect Vectors / virology
  • Italy / epidemiology
  • Mass Screening
  • Organ Transplantation / adverse effects
  • Population Surveillance
  • Risk
  • Transfusion Reaction / prevention & control
  • Transfusion Reaction / virology
  • Viremia / diagnosis
  • Viremia / epidemiology
  • West Nile Fever / diagnosis
  • West Nile Fever / epidemiology*
  • West Nile Fever / prevention & control
  • West Nile Fever / transmission
  • West Nile virus / isolation & purification