Keratoconus management has significantly changed over the last two decades. The advent of new interventions such as cornea cross-linking, intrastromal corneal ring segments, and combined treatments provide corneal clinicians a variety of treatment options for the visual rehabilitation of keratoconus patients. This review summarizes current evidence for these treatments and highlights their place in keratoconus management while new promising emerging therapies are being investigated.
Keywords: Accelerated cross-linking; CXL plus; Corneal cross-linking; Epi-on cross-linking; Intrastromal corneal ring segments; Keratoconus treatment algorithm.