Asthma Morbidity, Comorbidities, and Modifiable Factors Among Older Adults

J Allergy Clin Immunol Pract. 2018 Jan-Feb;6(1):236-243.e7. doi: 10.1016/j.jaip.2017.06.007. Epub 2017 Jul 26.

Abstract

Background: Asthma morbidity is increased among older adults, especially older adult women. Interventions to improve asthma control in this population are not well described.

Objective: The objective of this study was to identify risk factors (including modifiable factors) associated with asthma-related hospitalizations and emergency department or urgent care center visits (ED/UCV) among older adults. A secondary objective was to investigate sex differences in variables relevant to asthma control.

Methods: Data were obtained from 14,076 older adults ≥65 years with active asthma participating in the 2006-2010 Behavioral Risk Factor Surveillance System Asthma Call-back Survey (a random-digit dialed survey) in 40 US states, the District of Columbia, and Puerto Rico, representative of >2.6 million persons. Weighted, adjusted logistic regression was conducted.

Results: One or more asthma-related hospitalizations in the past year were reported by 5.7% (95% confidence interval [95% CI] = 5.0% to 6.4%) of participants; 10.6% (95% CI = 9.7% to 11.5%) reported ≥1 asthma-related ED/UCV. Compared with older adults without asthma-related hospitalizations, adjusted odds were higher among those with ≥1 asthma-related hospitalization for chronic obstructive pulmonary disease (COPD), coronary artery disease, depression, cockroaches or mold in the home, and cost barriers to asthma-related health care or medication. All these factors, except for cockroaches, were associated with asthma-related ED/UCV. Compared with males, adjusted odds were higher among females for COPD, depression, obesity, and cost barriers to asthma-related health care or medication.

Conclusions: Among older adults, asthma-related hospitalizations and ED/UCV were associated with clinical comorbidities, mold in the home, and financial barriers to asthma-related health care. Interventions addressing modifiable factors could reduce asthma morbidity among older adults.

Keywords: Asthma; Chronic obstructive pulmonary disease; Cockroach; Cost; Depression; Elderly; Environment; Health care utilization; Mold; Older adults.

MeSH terms

  • Age Factors*
  • Aged
  • Aged, 80 and over
  • Allergens / immunology
  • Animals
  • Asthma / epidemiology*
  • Cockroaches / immunology
  • Comorbidity
  • Coronary Artery Disease / epidemiology*
  • Depression / epidemiology*
  • Emergency Medical Services / statistics & numerical data
  • Female
  • Fungi / immunology
  • Health Services Accessibility
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Morbidity
  • Pulmonary Disease, Chronic Obstructive / epidemiology*
  • Risk Factors
  • Sex Factors
  • United States / epidemiology

Substances

  • Allergens