This overview presents nomenclature and serology information on human leucocyte antigens, or HLA molecules, which are encoded by a cluster of genes linked on the short arm of chromosome 6. This region is known as the major histocompatibility complex and codes for class I and class II molecules, which are distinguished from each other based upon their structure, tissue distribution, and source of peptide antigen, as well as upon their interactions with T cell subsets. © 2017 by John Wiley & Sons, Inc.
Keywords: HLA; HLA class I; HLA class II; MHC; human leucocyte antigens; major histocompatibility complex.
Copyright © 2017 John Wiley & Sons, Inc.