Excessive chemotherapy-related myelotoxicity in children with Down syndrome and acute lymphoblastic leukaemia

Lancet. 1986 Oct 18;2(8512):914. doi: 10.1016/s0140-6736(86)90429-0.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Agranulocytosis / chemically induced*
  • Antineoplastic Agents / adverse effects*
  • Bone Marrow / drug effects
  • Child
  • Child, Preschool
  • Down Syndrome / complications*
  • Humans
  • Leukemia, Lymphoid / drug therapy*
  • Methotrexate / adverse effects
  • Neutropenia / chemically induced*

Substances

  • Antineoplastic Agents
  • Methotrexate