Reweighted estimators for additive hazard model with censoring indicators missing at random

Lifetime Data Anal. 2018 Apr;24(2):224-249. doi: 10.1007/s10985-017-9398-z. Epub 2017 Aug 1.


Survival data with missing censoring indicators are frequently encountered in biomedical studies. In this paper, we consider statistical inference for this type of data under the additive hazard model. Reweighting methods based on simple and augmented inverse probability are proposed. The asymptotic properties of the proposed estimators are established. Furthermore, we provide a numerical technique for checking adequacy of the fitted model with missing censoring indicators. Our simulation results show that the proposed estimators outperform the simple and augmented inverse probability weighted estimators without reweighting. The proposed methods are illustrated by analyzing a dataset from a breast cancer study.

Keywords: Additive hazard model; Censored data; Inverse probability weighted estimator; Missing censoring indicators; Reweighting.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Bias*
  • Proportional Hazards Models*
  • Survival Analysis*