Executive summary: The Brain Injury and Mechanism of Action of Hyperbaric Oxygen for Persistent Post-Concussive Symptoms after Mild Traumatic Brain Injury (mTBI) (BIMA) Study

Undersea Hyperb Med. 2016 Aug-Sept;43(5):485-489.

Abstract

The Brain Injury and Mechanism of Action of Hyperbaric Oxygen for Persistent Post-Concussive Symptoms after Mild Traumatic Brain Injury (mTBI) (BIMA) study, sponsored by the Department of Defense and held under an investigational new drug application by the Office of the Army Surgeon General, is one of the largest and most complex clinical trials of hyperbaric oxygen (HBO₂) for post-concussive symptoms (PCS) in U.S. military service members.

Keywords: baseline; hyperbaric oxygen; mild traumatic brain injury; traumatic brain injury.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Blast Injuries / complications
  • Brain Concussion / complications*
  • Brain Concussion / physiopathology
  • Electroencephalography
  • Female
  • Heart Rate / physiology
  • Humans
  • Hyperbaric Oxygenation*
  • Male
  • Middle Aged
  • Military Personnel*
  • Neurologic Examination
  • Post-Concussion Syndrome / etiology
  • Post-Concussion Syndrome / physiopathology
  • Post-Concussion Syndrome / therapy*
  • Sleep Wake Disorders / diagnosis
  • Sleep Wake Disorders / etiology
  • Vestibular Diseases / diagnosis
  • Young Adult