Holding Onto Youth

Cell Metab. 2017 Aug 1;26(2):284-285. doi: 10.1016/j.cmet.2017.07.015.


Aerobic glycolysis (AG), the synthesis of lactate despite the presence of oxygen, has been implicated in the growth of cancer cells, synaptic development, and brain plasticity. In this issue of Cell Metabolism, Goyal et al. (2017) demonstrate that AG declines with age in the human brain, disappearing almost completely by age 60.

Publication types

  • Comment

MeSH terms

  • Brain*
  • Citric Acid Cycle
  • Glycolysis*
  • Humans
  • Lactic Acid


  • Lactic Acid