Chordoma arising from benign multifocal notochordal tumors

Skeletal Radiol. 2017 Dec;46(12):1745-1752. doi: 10.1007/s00256-017-2727-1. Epub 2017 Aug 3.


This case reports a 25-year-old woman initially diagnosed with adjacent benign notochordal cell tumors (BNCTs) of L3 and L4 based on needle biopsy of L3 and stable imaging over a 3-year period who was ultimately found to have a chordoma arising from a BNCT at L3. It illustrates the potential relationship between benign and malignant notochordal tumors and the difficulty in distinguishing them by clinical, radiological, and even histopathological means.

Keywords: Benign notochordal cell tumor; Chordoma; Lumbar; Multifocal; Spine; Vertebra.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy, Needle
  • Chordoma / diagnostic imaging*
  • Chordoma / pathology
  • Chordoma / therapy
  • Contrast Media
  • Electromyography
  • Female
  • Humans
  • Image-Guided Biopsy
  • Magnetic Resonance Imaging
  • Spinal Neoplasms / diagnostic imaging*
  • Spinal Neoplasms / pathology
  • Spinal Neoplasms / therapy
  • Tomography, X-Ray Computed


  • Contrast Media