Dioclins A and B, new antioxidant flavonoids from Dioclea reflexa

Nat Prod Res. 2018 Sep;32(17):2017-2024. doi: 10.1080/14786419.2017.1361949. Epub 2017 Aug 7.

Abstract

Dioclins A (1) and B (2), the new flavonoids, have been isolated from the ethyl acetate soluble fraction of the roots of Dioclea reflexa along with 3,5-dihydroxy-4 methoxybenzoic acid (3), lupeol (4) and the rare dipeptide, auratiamide acetate (5). Their structures have been elucidated by spectroscopic techniques. The compounds 1 and 2 showed a significant antioxidant activity in DPPH radical scavenging assay.

Keywords: Dioclea reflexa; Fabaceae; antioxidant activity; dioclins A–B; phytochemical.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Dioclea / chemistry*
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Plant Extracts / chemistry
  • Plant Roots / chemistry

Substances

  • Antioxidants
  • Flavonoids
  • Free Radical Scavengers
  • Plant Extracts