Linkage arrangement in the vitellogenin gene family of Xenopus laevis as revealed by gene segregation analysis

Nucleic Acids Res. 1986 Nov 25;14(22):8723-34. doi: 10.1093/nar/14.22.8723.

Abstract

Using restriction fragment length polymorphism (RFLP) we have analyzed the segregation of alleles of the different vitellogenin genes of Xenopus laevis. The results demonstrate that the four genes whose expression is controlled by oestrogen, form two linkage groups. The genes A1, A2 and B1 are linked genetically whereas the fourth gene, the gene B2, segregates independently. The possible origin of this unexpected arrangement is discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Animals
  • Crosses, Genetic
  • Female
  • Gene Frequency
  • Genes*
  • Genetic Linkage*
  • Genotype
  • Male
  • Polymorphism, Genetic*
  • Polymorphism, Restriction Fragment Length*
  • Vitellogenins / genetics*
  • Xenopus / genetics*

Substances

  • Vitellogenins