Enhanced cognition and emotional recognition, and reduced obsessive compulsive symptoms in two adults with high-functioning autism as a result of deep Transcranial Magnetic Stimulation (dTMS): a case report

Neurocase. 2017 Jun-Aug;23(3-4):187-192. doi: 10.1080/13554794.2017.1361451. Epub 2017 Aug 8.


We report reduced repetitive behaviors similar to obsessive compulsive disorder and improved emotional recognition and cognitive abilities in two young patients diagnosed with high-functioning Autism as a result of deep transcranial magnetic stimulation (dTMS). The patients received daily high-frequency (5 Hz) dTMS with HAUT-coil over the medial prefrontal cortex for a period of 5-6 weeks. A computerized cognitive battery, tasks for testing emotional recognition, and clinical questionnaires were used to measure the effects of treatment. TMS might have modulated networks related to metalizing abilities and self-referential processes since both patients reported improved sociability and communication skills.

Keywords: Autism; cognition; emotion; obsessive compulsive disorder; transcranial magnetic stimulation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Asperger Syndrome / complications
  • Asperger Syndrome / psychology*
  • Asperger Syndrome / therapy
  • Cognition*
  • Female
  • Humans
  • Male
  • Neuropsychological Tests
  • Obsessive-Compulsive Disorder / complications*
  • Prefrontal Cortex / physiopathology
  • Transcranial Magnetic Stimulation*