Proteinuria following trauma

Ann Clin Biochem. 1986 Nov:23 ( Pt 6):681-5. doi: 10.1177/000456328602300610.


Thirteen trauma patients admitted to a major injuries unit were classified according to their injury severity. Urinary excretion of total protein, albumin and gamma glutamyl transpeptidase (GGT) activity were assessed over the following 6 days. All patients showed an initial glomerular and tubular proteinuria during the first 24 h which subsided by the second post-trauma day. The excretion of total protein and albumin was positively correlated with injury severity. Those patients with the severest injuries showed a marked recurrent total proteinuria around days 3 to 4 post-trauma which exhibited features of a tubular lesion. The recurrent proteinuria peak coincided with peak levels of serum c-reactive protein (CRP).

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Albuminuria / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Proteinuria / etiology*
  • Time Factors
  • Wounds and Injuries / classification
  • Wounds and Injuries / complications*
  • Wounds and Injuries / urine
  • gamma-Glutamyltransferase / urine


  • gamma-Glutamyltransferase