1 Cardiothoracic Intensive Care Unit, National University Health System Singapore; and Paediatric Intensive Care Unit, Department of Paediatrics, Royal Children's Hospital, University of Melbourne, Melbourne, VIC, Australia Department of Paediatrics, National University Children's Medical Institute, National University Hospital, Singapore Department of Critical Care Medicine, Hospital for Sick Children; and Department of Anaesthesia, University of Toronto, Toronto, ON, Canada.