Abstract
Acute-phase serum samples collected during an outbreak of dengue fever and dengue haemorrhagic fever in Penang, Malaysia, were tested by a method involving antibody-dependent enhancement of infectivity in the mouse macrophage-like cell line, P388D1. 58 of 71 (81.7%) serologically positive cases yielded virus.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Viral / immunology*
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Dengue / epidemiology
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Dengue / immunology*
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Dengue Virus / isolation & purification*
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Dengue Virus / pathogenicity
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Disease Outbreaks
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Humans
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Macrophages / immunology
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Macrophages / microbiology*
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Malaysia
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Methods
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Mice