Clinical application of autogenous partially demineralized dentin matrix prepared immediately after extraction for alveolar bone regeneration in implant dentistry: a pilot study

Int J Oral Maxillofac Surg. 2018 Jan;47(1):125-132. doi: 10.1016/j.ijom.2017.02.1279. Epub 2017 Aug 10.

Abstract

The aim of this study was to examine the efficacy and safety of autogenous partially demineralized dentin matrix (APDDM) prepared onsite, for clinical application in bone regeneration procedures related to implant dentistry, including socket preservation, alveolar ridge augmentation, and maxillary sinus floor augmentation. In this study, 16 patients underwent dental implant placement using APDDM transplantation. There were no systemic or local complications (including surgical site infection) in any of the cases, and oral rehabilitation using dental implants was successful in all cases for at least 2 years after attachment of the suprastructure. This report describes the clinical application of APDDM prepared immediately after tooth extraction to bone augmentation, taking advantage of the relatively short preparation time due to partial demineralization. APDDM, as introduced in this study, is an efficient, safe, and reasonable bone substitute. Consequently, this material has the potential to become one of the options as a bone substitute in implant dentistry.

Keywords: alveolar bone augmentation; demineralized dentin matrix; implant dentistry.

MeSH terms

  • Adult
  • Alveolar Ridge Augmentation / methods*
  • Bone Regeneration / drug effects
  • Dental Implants*
  • Dentin*
  • Female
  • Humans
  • Immediate Dental Implant Loading*
  • Male
  • Middle Aged
  • Pilot Projects
  • Radiography, Panoramic
  • Tomography, X-Ray Computed
  • Tooth Extraction
  • Tooth Socket / surgery
  • Treatment Outcome

Substances

  • Demineralized Dentin Matrix
  • Dental Implants