Delirium in hospitalized patients: Risks and benefits of antipsychotics

Cleve Clin J Med. 2017 Aug;84(8):616-622. doi: 10.3949/ccjm.84a.16077.

Abstract

Consensus panel guidelines advocate for the judicious use of antipsychotic drugs to manage delirium in hospitalized patients when nonpharmacologic measures fail and the patient is in significant distress from symptoms, poses a safety risk to self or others, or is impeding essential aspects of his or her medical care. Here, we review the use of haloperidol, olanzapine, quetiapine, risperidone, and aripiprazole for this purpose.

Publication types

  • Review

MeSH terms

  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Aripiprazole / adverse effects
  • Aripiprazole / therapeutic use
  • Benzodiazepines / adverse effects
  • Benzodiazepines / therapeutic use
  • Delirium / drug therapy*
  • Haloperidol / adverse effects
  • Haloperidol / therapeutic use
  • Hospitalization
  • Humans
  • Olanzapine
  • Quetiapine Fumarate / adverse effects
  • Quetiapine Fumarate / therapeutic use
  • Risperidone / adverse effects
  • Risperidone / therapeutic use

Substances

  • Antipsychotic Agents
  • Benzodiazepines
  • Quetiapine Fumarate
  • Aripiprazole
  • Haloperidol
  • Risperidone
  • Olanzapine