Abstract
Acyclic nucleoside phosphonates have been prepared in a straightforward manner and in high yields by an enantioselective palladium-catalyzed allylic substitution involving nucleic bases as nucleophiles followed by cross-metathesis reaction with diethyl allylphosphonate.
MeSH terms
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Alkenes / chemistry*
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Amination
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Catalysis
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Chemistry Techniques, Synthetic
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Nucleosides / chemistry*
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Organophosphonates / chemical synthesis*
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Organophosphonates / chemistry*
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Palladium / chemistry*
Substances
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Alkenes
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Nucleosides
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Organophosphonates
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Palladium