Testosterone therapy improves erectile function and libido in hypogonadal men

Curr Opin Urol. 2017 Nov;27(6):511-515. doi: 10.1097/MOU.0000000000000442.


Purpose of review: Erectile dysfunction and decreased libido are common complaints in the older male population. Recent studies have elucidated the role testosterone therapy (TTh) can play in men with low testosterone levels. The aim of this review is to provide an overview of these findings and the utility of TTh. We specifically examine the role of TTh on erectile function, coadministration with phosphodiesterase type 5 inhibitors, and libido.

Recent findings: Recent publications suggest that TTh improves mild erectile dysfunction, though may be less useful in men with more severe erectile dysfunction. In men unresponsive to phosphodiesterase type 5 inhibitors and with mild erectile dysfunction, TTh can further improve erectile function. TTh has also shown consistent benefit in improving libido in men with low testosterone levels at baseline, with no additional improvements once testosterone levels are normalized.

Summary: The available literature supports a role for TTh in men with low testosterone levels, erectile dysfunction, and low libido, with symptomatic improvement in these men.

Publication types

  • Review

MeSH terms

  • Erectile Dysfunction / drug therapy*
  • Humans
  • Hypogonadism / blood
  • Hypogonadism / drug therapy*
  • Libido / drug effects*
  • Male
  • Penile Erection / drug effects*
  • Testosterone / physiology
  • Testosterone / therapeutic use*


  • Testosterone