Measurement of Cerebrospinal Fluid Flow Dynamics Using Phase Contrast MR Imaging with Bilateral Jugular Vein Compression: A Feasibility Study in Healthy Volunteers

Magn Reson Med Sci. 2018 Jul 10;17(3):265-268. doi: 10.2463/ Epub 2017 Aug 16.


We measured the changes in the cerebrospinal fluid (CSF) flow dynamics after compression of the bilateral jugular veins using phase contrast-magnetic resonance imaging (PC-MRI). PC-MRI was performed in 10 healthy male volunteers using a 3T clinical scanner with a two-dimensional gradient echo sequence. We successfully measured the changes in CSF flow velocity using PC-MRI with and without compression of the bilateral jugular veins. The relative velocity range decreased by about 30% when the bilateral jugular veins were compressed.

Keywords: cerebrospinal fluid; jugular vein; magnetic resonance imaging; phase contrast.

MeSH terms

  • Adult
  • Cerebrospinal Fluid / diagnostic imaging*
  • Cerebrospinal Fluid / physiology*
  • Cerebrospinal Fluid Pressure / physiology
  • Constriction
  • Feasibility Studies
  • Healthy Volunteers
  • Humans
  • Jugular Veins / diagnostic imaging*
  • Jugular Veins / physiopathology*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Reference Values
  • Young Adult