[Research progress of rapid detection of ochratoxin A and its application prospect in traditional Chinese medicine]

Zhongguo Zhong Yao Za Zhi. 2017 Jun;42(11):2032-2037. doi: 10.19540/j.cnki.cjcmm.20170224.008.
[Article in Chinese]

Abstract

Ochratoxin A (OTA) is a toxic secondary metabolite mainly produced by Aspergillus and Penicillium species, with strong renal toxicity, teratogenic, carcinogenic, mutagenic effect. Studies have shown that OTA is not only widely contaminated in food and feed crops, but also has been widely contaminated in Chinese herbal medicines such as spices, licorice and so on. In view of OTA's universality and harmfulness, this paper summarizes the flow visualization test strip, microsphere, electrochemical sensor, surface enhanced Raman spectroscopy technology in OTA rapid detection, which provides reference for the research and application of high throughout detection instrument miniaturization in order to achieve OTA quick detection and simple operation.

Keywords: Chinese medicine; rapid detection method; ochratoxin A.

Publication types

  • Review

MeSH terms

  • Drug Contamination*
  • Drugs, Chinese Herbal / standards*
  • Medicine, Chinese Traditional
  • Ochratoxins / isolation & purification*

Substances

  • Drugs, Chinese Herbal
  • Ochratoxins
  • ochratoxin A