Dietary factors in the etiology and therapy of attention deficit/hyperactivity disorder

Curr Opin Clin Nutr Metab Care. 2017 Nov;20(6):464-469. doi: 10.1097/MCO.0000000000000415.

Abstract

Purpose of review: The purpose of this study is to discuss the role of dietary factors in the etiology and therapy of attention deficit/hyperactivity disorder (ADHD). Relevant literature published from January 2016 to January 2017 was included in this review.

Recent findings: Unhealthy prenatal diet may be associated with ADHD in the offspring through an increase in epigenetic changes. The few-foods diet may have some efficacy, but requires further investigation before firm conclusions can be drawn. The efficacy of the supplementation of polyunsaturated fatty acids in the therapy of ADHD is probably small and may be confined to patient subgroups. It is unclear whether vitamin deficiency plays a role in the etiology of ADHD.

Summary: There is no clear evidence supporting a role of food or nutrient-based intervention strategies in the etiology and therapy of ADHD. The investigation of the inter-relationship between diet and other lifestyle interventions may be a promising approach.

Publication types

  • Review

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / diet therapy*
  • Attention Deficit Disorder with Hyperactivity / etiology
  • Avitaminosis / complications
  • Avitaminosis / diet therapy
  • Diet*
  • Dietary Supplements
  • Epigenesis, Genetic
  • Fatty Acids, Unsaturated / administration & dosage
  • Female
  • Gastrointestinal Microbiome
  • Humans
  • Life Style
  • Maternal Nutritional Physiological Phenomena
  • Pregnancy
  • Prenatal Care
  • Randomized Controlled Trials as Topic
  • Trace Elements / administration & dosage
  • Vitamins / administration & dosage

Substances

  • Fatty Acids, Unsaturated
  • Trace Elements
  • Vitamins