Successful ustekinumab treatment of noninfectious uveitis and concomitant severe psoriatic arthritis and plaque psoriasis

Cristina Mugheddu; Laura Atzori; Maria Del Piano; Astrid Lappi; Monica Pau; Severino Murgia; Ignazio Zucca; Franco Rongioletti

doi:10.1111/dth.12527

Successful ustekinumab treatment of noninfectious uveitis and concomitant severe psoriatic arthritis and plaque psoriasis

Dermatol Ther. 2017 Sep;30(5). doi: 10.1111/dth.12527. Epub 2017 Aug 18.

Authors

Cristina Mugheddu¹, Laura Atzori¹, Maria Del Piano², Astrid Lappi¹, Monica Pau¹, Severino Murgia¹, Ignazio Zucca³, Franco Rongioletti¹

Affiliations

¹ Department of Medical Science and Public Health, AOU of Cagliari, Dermatology Clinic, University of Cagliari, Cagliari, Italy.
² Reumatology, UO Medicine, Nuova Casa di Cura di Decimomannu, Cagliari, Italy.
³ Department of Surgical Science, Oculist Clinic, University of Cagliari, Cagliari, Italy.

PMID: 28833973
DOI: 10.1111/dth.12527

Abstract

We report the first successful treatment of noninfectious uveitis with ustekinumab in a patient with severe concomitant psoriasis and psoriatic arthritis who failed to respond to conventional immune suppressants and with contraindications to tumor necrosis factor alpha inhibitors.

Keywords: noninfectious uveitis; psoriasis; psoriatic arthritis; therapy; ustekinumab.

Publication types

Case Reports

MeSH terms

Arthritis, Psoriatic / drug therapy*
Arthritis, Psoriatic / pathology
Dermatologic Agents / therapeutic use
Female
Humans
Middle Aged
Psoriasis / drug therapy*
Psoriasis / pathology
Severity of Illness Index
Treatment Outcome
Ustekinumab / therapeutic use*
Uveitis / drug therapy*
Uveitis / pathology

Substances

Dermatologic Agents
Ustekinumab