Comparative analysis of diagnostic adequacy rate between aspiration and nonaspiration techniques of fine-needle cytology in patients with thyroid cancer and ultrasonographically suspicious cervical lymph nodes

Diagn Cytopathol. 2017 Oct;45(10):889-894. doi: 10.1002/dc.23793. Epub 2017 Aug 18.

Abstract

Background: We aimed to compare nonaspiration (NAS) and aspiration (AS) techniques in the evaluation of fine-needle cytology of lymph node (FNC-LN) in terms of diagnostic adequacy of cytologic material.

Methods: One hundred and twenty-three superficial cervical LNs in 75 patients who underwent NAS and AS-FNC-LN in the same visit were evaluated. Cytological results were categorized as diagnostic and nondiagnostic.

Results: The rates of malignancy were 13.8% in AS versus 16.3% in NAS technique, whereas nondiagnostic cytology was detected in 43.1% and 25.2%, respectively (P = .549 and P < .01).

Conclusions: The diagnostic adequacy rate in NAS-FNC-LN was significantly higher than AS-FNC-LN. However, NAS technique seems to be more simple and comfortable. We suggest both NAS and AS-FNC-LN in cytologic evaluation of suspicious cervical LNs until the diagnostic accuracy is determined with prospective studies.

Keywords: aspiration; diagnostic adequacy rate; fine-needle cytology; nonaspiration; suspicious lymph node.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Biopsy, Fine-Needle / methods
  • Biopsy, Fine-Needle / standards
  • Female
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Sentinel Lymph Node Biopsy / methods*
  • Sentinel Lymph Node Biopsy / standards
  • Thyroid Neoplasms / diagnostic imaging
  • Thyroid Neoplasms / pathology*
  • Ultrasonography