Extrapolation or controlled trials in paediatrics: the current dilemma

Arch Dis Child. 2017 Oct;102(10):949-951. doi: 10.1136/archdischild-2017-312994. Epub 2017 Aug 26.

Authors

Nicolino Ruperto¹, Hermine I Brunner², Daniel J Lovell², Alberto Martini³, Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)

Affiliations

¹ Pediatria II, Reumatologia-PRINTO, IRCCS Giannina Gaslini, Genova, Italy.
² Division of Rheumatology-PRCSG, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
³ Direzione Scientifica, IRCCS Giannina Gaslini, Genova, Italy.

PMID: 28844066
DOI: 10.1136/archdischild-2017-312994

No abstract available

Keywords: clinical trials; extrapolation; pediatrics; rheumatology.

MeSH terms

Child
Clinical Trials as Topic*
Female
Humans
Male
Pediatrics*
Rheumatology