Spiradenoma

Excerpt

Spiradenomas are well-differentiated, benign, dermal neoplasms originating from the sweat glands. Most spiradenomas occur between the ages of 15 to 35 years. Typically, they present as small solitary nodules that can grow to several centimeters, often with a blue, gray, or purple hue. They are strikingly painful. Spiradenomas usually arise on the head, neck, and trunk; however, cases have occurred in other areas, such as the breast. Spiradenomas with varying morphology, like multiple linear, zosteriform, blaschkoid, and nevoid spiradenomas, have also been reported. Spiradenomas can occur concomitantly with cylindromas, trichoepitheliomas, or trichoblastomas. Multiple spiradenomas, cylindromas, and trichoepitheliomas can be seen in patients with Brooke-Spiegler.