Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Mar;33(3):247-254.
doi: 10.14670/HH-11-926. Epub 2017 Aug 29.

Ecology of Melanoma Cell

Affiliations
Review

Ecology of Melanoma Cell

Lukáš Lacina et al. Histol Histopathol. .

Abstract

Melanoma represents a cancer with increasing incidence worldwide and limited curability of advanced stages of the disease. Similarly to other types of tumors, the microenvironment is an important factor that participates in the control of melanoma biological properties. This review summarizes data regarding the role of the microenvironment, namely fibroblasts, keratinocytes and infiltrating immune cells, on melanoma growth and spreading. The role of embryonic microenvironment on melanoma cell biological properties is also discussed. The potential of therapeutic targeting of the melanoma microenvironment is demonstrated.

Similar articles

See all similar articles

Cited by 2 articles

LinkOut - more resources

Feedback