Distribution of HBV genotypes in Poland

Clin Exp Hepatol. 2015 May;1(1):1-4. doi: 10.5114/ceh.2015.51372. Epub 2015 Apr 30.


Aim of the study: To identify distribution of HBV genotypes in particular regions of Poland.

Material and methods: The study included 270 treatment-naïve, HBV-infected individuals, enrolled in 7 centers of Poland. HBV genotyping was performed in 243 of them with the INNO-LiPA HBV Genotyping assay (Innogenetics).

Results: Genotype A present in 2/3 patients was demonstrated as the most predominant in Poland. It was followed by D (20%), H (5%) and mixed A + D (5%). Remaining patients were infected with genotype F, mixed D + G, A + C or D + F. Analysis of distribution demonstrated regional differences, with a higher rate of genotype D prevalence (about 30%) in the eastern (Białystok and Lublin) and south-western (Wrocław) parts compared to other regions, where the prevalence rate was below 15%. The highest prevalence of genotype A (exceeding 80%) was observed in central Poland (Bydgoszcz, Łódź).

Conclusions: The presented data reveal the current distribution of HBV genotypes across Poland, which is the first and the largest such epidemiological analysis.

Keywords: HBV; epidemiology; genotypes; hepatitis.