Assessment of Thoracic Ultrasound in Complementary Diagnosis and in Follow Up of Community-Acquired Pneumonia (Cap)

BMC Med Imaging. 2017 Aug 31;17(1):52. doi: 10.1186/s12880-017-0225-5.


Background: Chest X-ray (CXR) is the primary diagnostic tool for community-acquired pneumonia (CAP). Some authors recently proposed that thoracic ultrasound (TUS) could valuably flank or even reliably substitute CXR in the diagnosis and follow-up of CAP. We investigated the clinical utility of TUS in a large sample of patients with CAP, to challenge the hypothesis that it may be a substitute for CXR.

Methods: Out of 645 consecutive patients with a CXR-confirmed CAP diagnosed in the emergency room of our hospital over a three-years period, 510 were subsequently admitted to our department of Internal Medicine. These patients were evaluated by TUS by a well-trained operator who was blinded of the initial diagnosis. TUS scans were performed both at admission and repeated at day 4-6th and 9-14th during stay.

Results: TUS identified 375/510 (73.5%) of CXR-confirmed lesions, mostly located in posterior-basal or mid-thoracic areas of the lungs. Pleural effusion was detected in 26.9% of patients by CXR and in 30.4% by TUS. TUS documented the change in size of the consolidated areas as follows: 6.3 ± 3.4 cm at time 0, 2.5 ± 1.8 at 4-6 d, 0.9 ± 1.4 at 9-14 d. Out of the 12 patients with delayed CAP healing, 7 of them turned out to have lung cancer.

Conclusions: TUS allowed to detect lung consolidations in over 70% of patients with CXR-confirmed CAP, but it gave false negative results in 26.5% of cases. Our longitudinal results confirm the role of TUS in the follow-up of detectable lesions. Thus, TUS should be regarded as a complementary and monitoring tool in pneumonia, instead of a primary imaging modality.

Keywords: Community acquired pneumonia (CAP); Complementary diagnostic tool; Follow-up; Thoracic ultrasound (TUS).

MeSH terms

  • Adult
  • Aged
  • Community-Acquired Infections / diagnosis
  • False Negative Reactions
  • Female
  • Humans
  • Inpatients
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Pneumonia / diagnosis*
  • Sensitivity and Specificity
  • Thorax / diagnostic imaging*
  • Ultrasonography