Improvements in cardiometabolic risk markers, aerobic fitness, and functional performance following a physical therapy weight loss program

Physiother Theory Pract. 2018 Jan;34(1):13-21. doi: 10.1080/09593985.2017.1368757. Epub 2017 Sep 1.

Abstract

Objective: The objectives of this study were to determine the efficacy of a current physical therapy and weight loss program model on exercise performance, physical function, and cardiometabolic risk factors in obese patients.

Design: Retrospective pre-post design.

Subjects: A total of 192 patients who previously underwent testing of anthropometric measurements, cardiovascular biomarkers, and lower extremity function scale (LEFS) were included.

Results: There was a significant reduction in body weight [5.91 ± 3.47 (95% CI, 5.4 to 6.4) kg; p < 0.001; n = 187] and waist circumference [7.1 ± 5 (95% CI, 6.3 to 7.9) cm; p < 0.001; n = 187]. Submaximal exercise capacity (VO2ex) increased by [5.29 ± 4.74 (95% CI, 4.38 to 6.19) ml/kg/min; p < 0.001; n = 107], and lower extremity functional scale (LEFS) improved by [9 ± 11 (95% CI, 7 to 12) scale points; p < 0.001; n = 75]. Both systolic (pre SBP: 125.7 ± 15 vs. post SBP: 118.4 ± 12 mmHg; p < 0.001; n = 150) and diastolic (pre DBP: 78.5 ± 10 vs. post DBP: 74 ± 8.5 mmHg; p < 0.001; n = 150) blood pressures as well as fasting blood glucose (pre FBG: 112.8 ± 37 vs. post FBG: 99 ± 18 mg/dL; p < 0.001; n = 132) were significantly reduced.

Conclusions: This study indicates the importance and significance of weight loss in improving physical function and cardiometabolic risk profiles across a cohort of outpatient physical therapy patients. Our study also suggests that weight loss can be achieved in a comprehensive exercise intensive physical therapy program for obese patients.

Keywords: Biomarkers; obesity; physical therapy; risk factors; weight loss.

MeSH terms

  • Adult
  • Aged
  • Biomarkers / blood
  • Blood Glucose / metabolism
  • Blood Pressure
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / prevention & control*
  • Cross-Sectional Studies
  • Exercise Tolerance
  • Female
  • Health Status
  • Humans
  • Male
  • Middle Aged
  • Obesity / complications
  • Obesity / diagnosis
  • Obesity / physiopathology
  • Obesity / therapy*
  • Physical Fitness*
  • Physical Therapy Modalities*
  • Recovery of Function
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Waist Circumference
  • Weight Loss*
  • Weight Reduction Programs / methods*

Substances

  • Biomarkers
  • Blood Glucose