Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals

J Neurol Neurosurg Psychiatry. 2018 Apr;89(4):439-441. doi: 10.1136/jnnp-2017-316234. Epub 2017 Sep 2.

Affiliations

¹ Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
² Department of Biomedical and Specialist Surgical Sciences, Section of Neurological, Psychiatric and Psychological Sciences, University of Ferrara, Ferrara, Italy.

^# Contributed equally.

PMID: 28866627
DOI: 10.1136/jnnp-2017-316234

No abstract available

Keywords: Molecular Biology; Multiple Sclerosis; Neurobiology; Neuropathology.

Publication types

Letter

MeSH terms

Adult
Aged
Autophagy*
Autophagy-Related Protein 5 / blood
Autophagy-Related Protein 5 / cerebrospinal fluid*
Case-Control Studies
Female
Humans
Male
Middle Aged
Mitophagy*
Multiple Sclerosis, Relapsing-Remitting / blood
Multiple Sclerosis, Relapsing-Remitting / cerebrospinal fluid*
Multiple Sclerosis, Relapsing-Remitting / immunology
Nervous System Diseases / blood
Nervous System Diseases / cerebrospinal fluid
Nervous System Diseases / immunology
Tumor Necrosis Factor-alpha / blood
Tumor Necrosis Factor-alpha / cerebrospinal fluid
Ubiquitin-Protein Ligases / blood
Ubiquitin-Protein Ligases / cerebrospinal fluid*
Young Adult

Substances

ATG5 protein, human
Autophagy-Related Protein 5
TNF protein, human
Tumor Necrosis Factor-alpha
Ubiquitin-Protein Ligases
parkin protein