The developing world of DOHaD

J Dev Orig Health Dis. 2018 Jun;9(3):266-269. doi: 10.1017/S2040174417000691. Epub 2017 Sep 5.


Since its debut in a ground-breaking report by Barker and Osmond in 1986, the concept of the Developmental Origins of Health and Disease (DOHaD) has been further developed in several aspects. Its methodology and conclusions relating to proposed origins and outcomes of early life events have been developing and spreading internationally. Indeed, the DOHaD concept now seems to have influenced many fields of research. This article aims to briefly review why the DOHaD concept is important in biomedical science, how it has developed, is currently developing, and how it should develop in future.

Keywords: animal; developmental stage; epidemiology/public health; human; molecular/cellular; outcome/system; policy/economics.

Publication types

  • Review

MeSH terms

  • Biomedical Research*
  • Developmental Disabilities / physiopathology*
  • Female
  • Health Behavior
  • Humans
  • Nutritional Sciences*
  • Pregnancy
  • Prenatal Exposure Delayed Effects*