Magnetic graphene sol-gel hybrid as clean-up adsorbent for acrylamide analysis in food samples prior to GC-MS

Hamid Rashidi Nodeh; Wan Aini Wan Ibrahim; Muhammad Afzal Kamboh; Mohd Marsin Sanagi

doi:10.1016/j.foodchem.2017.06.094

Magnetic graphene sol-gel hybrid as clean-up adsorbent for acrylamide analysis in food samples prior to GC-MS

Food Chem. 2018 Jan 15:239:208-216. doi: 10.1016/j.foodchem.2017.06.094. Epub 2017 Jun 19.

Authors

Hamid Rashidi Nodeh¹, Wan Aini Wan Ibrahim², Muhammad Afzal Kamboh³, Mohd Marsin Sanagi⁴

Affiliations

¹ Separation Science and Technology Group, Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia; Department of Chemistry, Faculty of Science, University of Tehran, Tehran, Iran.
² Separation Science and Technology Group, Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia; Centre for Sustainable Nanomaterials, Ibnu Sina Institute for Scientific and Industrial Research, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia. Electronic address: wanaini@kimia.fs.utm.my.
³ Separation Science and Technology Group, Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia; Department of Chemistry, Shaheed Benazir Bhutto University, Shaheed Benazirabad, Sindh, Pakistan.
⁴ Separation Science and Technology Group, Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia; Centre for Sustainable Nanomaterials, Ibnu Sina Institute for Scientific and Industrial Research, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia.

PMID: 28873561
DOI: 10.1016/j.foodchem.2017.06.094

Abstract

Graphene (G) modified with magnetite (Fe₃O₄) and sol-gel hybrid tetraethoxysilane-methyltrimethoxysilane (TEOS-MTMOS) was used as a clean-up adsorbent in magnetic solid phase extraction (MSPE) for direct determination of acrylamide in various food samples prior to gas chromatography-mass spectrometry analysis. Good linearity (R²=0.9990) was achieved for all samples using matrix-matched calibration. The limit of detection (LOD=3×SD/m) obtained was 0.061-2.89µgkg^-1 for the studied food samples. Native acrylamide was found to be highest in fried potato with bright-fleshed (900.81µgkg^-1) and lowest in toasted bread (5.02µgkg^-1). High acrylamide relative recovery (RR=82.7-105.2%) of acrylamide was obtained for spiked (5 and 50µgkg^-1) food samples. The Fe₃O₄@G-TEOS-MTMOS is reusable up to 7 times as a clean-up adsorbent with good recovery (>85%). The presence of native acrylamide was confirmed by mass analysis at m/z=71 ([C₃H₅NO]⁺) and m/z=55 ([C₃H₃O]⁺).

Keywords: Acrylamide; Clean-up; Food samples; GC–MS; Graphene-based sol–gel hybrid adsorbent; Magnetic solid phase extraction.

MeSH terms

Acrylamide / analysis*
Food Analysis
Gas Chromatography-Mass Spectrometry
Graphite
Magnetics
Solid Phase Extraction

Substances

Acrylamide
Graphite