Oral mucormycosis in patients with haematologic malignancies in a bone marrow transplant unit

Mycoses. 2017 Dec;60(12):836-841. doi: 10.1111/myc.12678. Epub 2017 Sep 6.

Abstract

Mucormycosis is an aggressive and life-threatening opportunistic fungal infection, which predominantly affects immunocompromised patients. It typically manifests in rhinocerebral, pulmonary or disseminated forms in patients with immunosuppressive conditions. Mucormycosis limited to the oral cavity is rare, and to the best of our knowledge only seven cases have previously been reported in English literature. We present five consecutive cases of oral mucormycosis in patients with leukaemia, and provide a literature review.

Keywords: bone-marrow transplant unit; leukaemia; mucormycosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Antifungal Agents / administration & dosage
  • Bone Marrow Transplantation
  • Female
  • Humans
  • Leukemia / complications*
  • Leukemia / therapy
  • Male
  • Middle Aged
  • Mouth Diseases / drug therapy
  • Mouth Diseases / etiology*
  • Mucormycosis / drug therapy
  • Mucormycosis / etiology*

Substances

  • Antifungal Agents