Left Ventricular Noncompaction Cardiomyopathy Presenting with Heart Failure in a 35-Year-Old Man

Tex Heart Inst J. 2017 Aug 1;44(4):260-263. doi: 10.14503/THIJ-15-5371. eCollection 2017 Aug.


Isolated ventricular noncompaction, a rare genetic cardiomyopathy, is thought to be caused by the arrest of normal myocardial morphogenesis. It is characterized by prominent, excessive trabeculation in a ventricular wall segment and deep intertrabecular recesses perfused from the ventricular cavity. The condition can present with heart failure, systematic embolic events, and ventricular arrhythmias. Two-dimensional echocardiography is the typical diagnostic method. We report a case of heart failure in a 35-year-old man who presented with palpitations. Two-dimensional echocardiograms revealed left ventricular noncompaction, which markedly improved after standard heart failure therapy.

Keywords: Cardiomyopathies/diagnosis/prevention & control; heart defects, congenital/diagnostic imaging; heart failure/etiology; heart ventricles/abnormalities/diagnostic imaging; isolated noncompaction of the ventricular myocardium/complications/diagnostic imaging/drug therapy; treatment outcome; ventricular dysfunction, left/etiology.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Adult
  • Cardiomyopathy, Dilated / complications*
  • Cardiomyopathy, Dilated / diagnostic imaging
  • Cardiomyopathy, Dilated / drug therapy
  • Cardiomyopathy, Dilated / physiopathology
  • Cardiovascular Agents / therapeutic use
  • Heart Failure / diagnostic imaging
  • Heart Failure / drug therapy
  • Heart Failure / etiology*
  • Heart Failure / physiopathology
  • Heart Rate
  • Humans
  • Isolated Noncompaction of the Ventricular Myocardium / complications*
  • Isolated Noncompaction of the Ventricular Myocardium / diagnostic imaging
  • Isolated Noncompaction of the Ventricular Myocardium / drug therapy
  • Isolated Noncompaction of the Ventricular Myocardium / physiopathology
  • Magnetic Resonance Imaging
  • Male
  • Recovery of Function
  • Therapeutics
  • Ventricular Function, Left


  • Cardiovascular Agents